肿瘤体积和放疗剂量对局部晚期非小细胞肺癌预后的影响分析

Analysis the Gross Tumor Volume and Radiotherapy Dose Prognostic Impact for Locally Advance Non-small Cell Lung Cancer

目的：观察并探讨肿瘤体积和放疗剂量对局部晚期非小细胞肺癌预后的影响。方法选择2014年4月～2015年5月本院收治的90例局部晚期非小细胞肺癌患者为研究对象，根据CT扫描系统以及三维适形放射治疗的计划系统制作相应的3个靶区，分别命名为GTV-N、GTV-P以及GTV-T，研究并分析每个靶区里肿瘤体积和放疗剂量对局部晚期非小细胞肺癌预后的影响。结果 GTV-T小于100.00 cm^3患者的生存率高于GTV-T大于100.00 cm^3患者，P＜0.05，差异具有统计学的意义。结论运用CT扫描系统以及三维适形放射治疗的计划系统治疗局部晚期非小细胞肺癌时，适当增加放疗的剂量有利于预后。

Objective Observation and explore the effect of tumor volume and radiotherapy dose on the prognosis of locally advanced non-small cell lung cancer. Methods Selected 90 cases with locally advanced non-small cell lung cancer from April 2014 to May 2015 as the object, according to the CT scanning system and three-dimensional conformal radiation therapy planning system making three corresponding target area, named for. And GTV-P and GTV-T, research and analyed of each target district tumor volume and dose of radiotherapy for locally advanced non influence the prognosis of small cell lung cancer. Results The survival rate of patients with GTV-T less than 100 GTV-T was higher than that of patients with cm^3 greater than 100 cm^3, P〈0.05, had difference statistically signiifcance. Conclusion Use CT scanning system and three-dimensional conformal radiation treatment planning system in treatment of locally advanced non small cell lung cancer, appropriate increase in radiation dose is conducive to the patient＇s prognosis.