肺表面活性物质治疗新生儿呼吸窘迫综合征的疗效观察

To Observe the Curative Effect of Pulmonary Surfactant Treatment Neonatal Respiratory Distress Dyndrome

目的：探讨肺表面活性物质治疗新生儿呼吸窘迫综合征的疗效。方法选取52例呼吸窘迫综合征患儿进行研究，随机分为观察组和对照组，各26例。观察组给予肺表面活性物质治疗，对照组给予常规治疗。结果观察组治疗2～3 h后皮肤颜色转红，TcSO2逐渐升高，6 h后PaO2及a/APO2的比值升高，而OI值降低。对照组治疗后PaO2及a/APO2的比值有所升高，OI降低。观察组机械通气及氧疗时间与对照组相比缩短，P＜0.05，差异具有统计学意义。结论肺表面活性物质治疗新生儿呼吸窘迫综合征疗效显著。

Objective To investigate the curative effect of pulmonary surfactant treatment neonatal respiratory distress dyndrome. Methods Selected 52 cases with respiratory distress syndrome, Randomly divided into the observation group and the control group, each group had 26 cases. The observation group received the treatment of pulmonary surfactant, The control group was treated with conventional therapy. Results After treatment, the skin color turned red and TcSO2 gradually increased in the observation group after treatment with 2 to 3 hours, After PaO2, the ratio of 6 h and a/APO2 increased obviously, and the OI value was signiifcantly decreased. The ratio of a/APO2 and PaO2 in control group was increased, and OI was not obvious. The observation group mechanical ventilation and oxygen therapy time was shorter than the control group. P〈0.05, had difference statistically significance. Conclusion Pulmonary surfactant in treatment of neonatal respiratory distress syndrome has signiifcant curative effect.