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血清CEA和CA-199对卡培他滨治疗复发转移乳腺癌预后的临床预测 被引量:3

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摘要 目的分析血清CEA和CA-199对卡培他滨治疗复发转移乳腺癌预后的临床预测价值。方法选取我院2011年3月至2013年3月到我院就诊的27例复发转移乳腺癌患者,均予以卡培他滨治疗,动态检测患者化疗前后的血清CEA和CA-199,分析CEA和CA-199两项指标与患者总生存时间和无进展生存期的关系。结果 1患者化疗前血清CEA和CA-199基线水平对患者的OS和PFS无影响;2患者化疗后血清CEA和CA-199下降明显者(≥25%)的OS、PFS与无下降或下降不明显者(<25%)差异均较大(P<0.05)。结论通过检测复发转移乳腺癌患者化疗前后血清CEA和CA-199,分析其下降率,可以有效预测患者的生存情况,具有较高的临床应用和推广价值。
作者 刘桂芹
出处 《哈尔滨医药》 2015年第3期205-206,共2页 Harbin Medical Journal
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