早泄诊断量表的汉化研究和信效度评价

Reliability and validity of the Chinese version of The Premature Ejaculation Diagnostic Tool

目的:对英文版早泄诊断量表(PEDT)进行汉化,并评价PEDT量表的信度和效度,分析其在早泄诊断的可行性。方法:首先对PEDT量表进行翻译、回译和审议修订,在全国15家泌尿外科或者男科门诊选取早泄患者填写受试者的一般情况、PEDT量表和阴道内射精潜伏时间(IELT),并以性功能正常男性填写此量表作为对照。采用Cronbach's alpha检验PEDT量表内部一致性,采用test-retest检验评价PEDT量表的重测信度和稳定性,并分析PEDT量表与IELT的相关性以及PEDT量表的敏感性和特异性。结果:本研究共有570例早泄患者[年龄(30.66±7.11)岁]和226例正常男性[年龄(33.01±5.41)岁]参与,其中早泄组和正常组的IELT分别为(1.34±0.54)min和(11.09±7.5)min。PEDT量表的Cronbach's alpha系数为0.79,重测信度为0.75(P<0.01);PEDT量表评分与IELT之间存在显著的负相关性(Spearman'sρ=-0.52,P<0.01);当诊断早泄的切点值为7.5时,PEDT量表的敏感性和特异性分别为0.80和0.78;当诊断早泄的切点为8.5时,PEDT量表的敏感性和特异性分别为0.72和0.89。结论:PEDT量表中文汉化版具有良好的内部一致性、信度和效度,对我国早泄患者有良好的预测能力,为早泄的临床评估应用提供了一个可靠、简便的测量工具。

Objective： To translate the English version of The Premature Ejaculation Diagnostic Tool（ PEDT） into Chinese,evaluate its reliability and validity,and analyze its feasibility in the diagnosis of premature ejaculation（ PE）. Methods： Following the forward-backward translation procedure,we developed the Chinese version of PEDT,which was then revised by andrologists and bilingual linguists. We enrolled subjects with or without PE from 15 urological or andrological clinics in China and obtained the information about their demographic characteristics,PEDT scores,and intra-vaginal ejaculation latency time（ IELT）. We evaluated the internal consistency of PEDT using Cronbach＇s alpha,was examined its reliability and stability by test-retest analysis,analyzed its correlation with IELT by Spearman correlation analysis,and tested its sensitivity and specificity by receiver operating characteristic（ ROC）analysis. Results： Totally,570 PE patients（ aged [30. 66 ± 7. 11]years） and 226 non-PE men（ aged [33. 01 ± 5. 41]years） were recruited,with the mean IELT of（ 1. 34 ± 0. 54） min in the former and（ 11. 09 ± 7. 5） min in the latter group. The Cronbach＇s alpha of the Chinese version of PEDT was 0. 79,and the test-retest correlation coefficient was 0. 75（ P〈0. 01）. The PEDT score was negatively correlated with IELT（ Spearman＇s ρ =- 0. 52,P〈0. 01）. When the cutoff value of PE diagnosis was defined as 7. 5,the sensitivity and specificity of PEDT were 0. 80 and 0. 78,and when as 8. 5,they were 0. 72 and 0. 89,respectively. Conclusion： The Chinese version of PEDT was demonstrated to have good internal consistency,reliability,and validity,as well as a high predictability for PE. It can be used as a reliable and convenient tool to screen PE among Chinese men.