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根治性前列腺切除术和放射疗法治疗高危前列腺癌的研究进展 被引量:4

Radical prostatectomy and radiation therapy for high-risk prostate cancer: An update
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摘要 目前,临床上对高危前列腺癌(PCa)的定义尚未统一,但其中D'Amico危险分层系统更为学界所接受。其对高危PCa的定义为PSA〉20μg/L,Gleason评分8~10分,临床分期≥T2c。由于高危PCa在治疗后易复发和转移,因此选择合适的治疗方案成为关键。目前针对高危PCa最重要的一线治疗方法为根治性前列腺切除术(RP)或放射治疗(RT),然而其最佳治疗方案仍未达成共识。本文综述RP和RT治疗高危PCa的研究进展。 Recently,the D'Amico classification system is widely used for the risk stratification of prostate cancer( PCa),although no consensus has been reached for the definition of high-risk PCa. This system defines high-risk PCa as a prostate-specific antigen( PSA) level 20 ng / ml,a Gleason score of 8- 10,or a clinical stage ≥ T2 c. Because high-risk PCa is prone to recurrence and metastasis after treatment,a proper initial therapy plays a crucial role. Currently,radical prostatectomy and radiation therapy are considered to be two most important options for the initial treatment of high-risk PCa although it remains controversial which is better.
出处 《中华男科学杂志》 CAS CSCD 北大核心 2015年第7期663-666,共4页 National Journal of Andrology
基金 国家自然科学基金(81370855 30901484)~~
关键词 高危前列腺癌 根治性前列腺切除术 放射疗法 high-risk prostate cancer radical prostatectomy radiation therapy
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