星状神经节置管及间断阻滞对治疗突发性聋的效果及安全性评价

Stellate ganglion catheter retention with discontinuous block on efficacy and safety in the treatment of sudden deafness

目的:探讨星状神经节保留置管配合间断阻滞对治疗突发性聋的疗效及安全性。方法:选择突发性单侧聋患者126例,按随机分组原则分为置管组、阻滞组、对照组各42例,3组均常规给扩管药物、糖皮质激素和高压氧综合治疗,置管组应用星状神经节穿刺后留置导管,罗哌卡因阻滞1次/d;阻滞组1次/d,星状神经节穿刺并罗哌卡因阻滞;对照组只应用综合治疗。置管组和阻滞组均在阻滞治疗后再行高压氧治疗。观察3组治疗效果、患者满意度、阻滞前及5min后心率、血压的变化,记录有无脱管及药物不良反应。结果:置管组、阻滞组总有效率(85.7%、83.3%)明显高于对照组[64.3%(27例),P<0.05],置管组患者满意率(83.3%)明显高于阻滞组61.9%(26例),P<0.05]。置管组与阻滞组首次置管前、5min后心率、血压的均变化明显,无药物不良反应和脱管事件发生。结论:应用星状神经节保留置管配合间断罗派卡因阻滞,取得了较好的治疗效果,是安全有效的治疗方法。

Objective：To investigate effect and safty evaluation of stellate ganglion catheter retention with discontinuous block on sudden deafness.Method：One hundred and twenty-six patiens with sudden monaural deafness were randomly divided into Catheterp and block and control groups with 42 cases in each group.All patients＇ throats were given conventional blood activating drugs,hormone and hyperbaric oxygen therapy.stellate ganglion puncture retained catheter were administrated to the patients in catheter group followed by ropivacaine block 1times/day,block group stellate ganglion puncture and ropivacaine block 1times/day.The patients in control group were only received routine comprehensive treatment.Patients in both catheter group and block groups were treated by hyperbaric oxygen therapy after the block treatment.Curative effects of three groups were observed.The patients′satisfaction,heart rate,the chages of blood pressure before and after the block,detachment of tubes,and adverse drug reaction were recorded.Result：The effect of the treatment in bothcatheter group,block group was better than in control group（85.7%,37cases）;83.3%,35cases）vs 64.3%,27 cases,P〈0.05）.The satisfactory rate in the patients in catheter group was significantly higher than block group（83.3%,35 cases vs 61.9%,26 cases,P〈0.05）.the heart rate and the blood pressure before and 5minutes after catheterization in catheter group and block groupwere changed obviously.Moreover,no adverse drug reaction and detachment of tubeswere observed.Conclusion：It is a safe and effective administration of stellate ganglion catheter retention with interrupted ropivacaine block.