氟喹诺酮类抗生素治疗呼吸道支原体感染的疗效观察

Clinical Application and Effi cacy Observation of New Fluoroquinolone Antibiotic to Treat Respiratory Mycoplasma Infection

目的:探讨新氟喹诺酮类抗生素治疗呼吸道支原体感染的临床治疗效果和不良反应。方法:选取2013年1月-2014年12月东莞市寮步医院收治的100例呼吸道支原体感染患者作为研究对象,随机分为对照组和观察组,每组50例。对照组使用阿奇霉素治疗,观察组患者使用新氟喹诺酮类抗生素治疗。治疗2周后,观察对照组和观察组的临床治疗效果和不良反应发生情况。结果:治疗后,对照组临床治疗总有效率为82%,观察组临床治疗总有效率为96%,观察组临床治疗效果和不良反应发生情况明显优于对照组,差异有统计学意义(P<0.05)。结论:新氟喹诺酮类抗生素治疗呼吸道支原体感染,不仅具有显著的疗效,还具有较高的安全性,临床应用价值高。

Objective To observe clinical therapeutic effect and adverse reactions of the new fluoroquinolone antibiotics on treating respiratory tract mycoplasma infection. Methods： 100 cases of patients from January 2013 to December 2014 in our hospital treated with respiratory tract mycoplasma infection were selected as the research object, which were randomly divided into control group and observation group, 50 cases in each group. The control group used azithromycin treatment, the observation group of patients using new fluoroquinolone antibiotics. 2 weeks after treatment, the clinical therapeutic effect of the control group and observation group and the adverse reactions occurring were observed and compared. Results： After treatment, the total effective rate for control group was 82%, for observation group was 96%, and the clinical therapeutic effect and adverse reaction for observation group was better than control group, the difference was statistically significant（P〈 0.05）. Conclusion： The new fluoroquinolone antibiotics for respiratory tract mycoplasma infection, not only has significant curative effect, also has high security, high clinical value.