鼻塞持续气道正压通气治疗新生儿危重呼吸病低氧血症的效果观察

Therapeutic effect of nasal continuous positive airway pressure ventilation on treatment of neonates with severe respiratory disease and hypoxaemia

目的了解鼻塞持续气道正压通气治疗新生儿危重呼吸病低氧血症的效果,并总结其护理经验。方法对30例危重呼吸病低氧血症新生儿采用鼻塞持续气道正压通气治疗,并实施相应的护理。观察鼻塞持续气道正压通气治疗前和治疗24 h后患儿动脉血氧分压(arterial partial pressure of oxygen,Pa O2),二氧化碳分压(partial pressure of carbon dioxide,PCO2),氧合指数(carterial oxygen tension,Pa O2/Fi O2)和p H值。结果鼻塞持续气道正压通气治疗后新生儿Pa O2、PCO2、Pa O2/Fi O2和p H值均优于正压通气治疗前,治疗前后比较,差异均有统计学意义(P<0.05)。结论鼻塞持续气道正压通气对新生儿危重呼吸病低氧血症具有良好的治疗效果。做好通气压力调节,新生儿鼻部皮肤及黏膜的保护,预防呕吐等护理对保证持续气道正压通气治疗效果具有积极的意义。

Objective To explore the effect of nasal continuous positive airway pressure ventilation on severe respiratory disease and hypoxaemia. Methods In 30 neonates with severe respiratory disease-induced hypoxemia were managed with nasal continuous positive airway pressure, and corresponding nursing. Nasal continuous positive airway pressure before and after treatment,24 h arterial partial pressure of oxygen（Pa O2）, partial pressure of carbon dioxide（PCO2）, Pa O2/ Fi O2 and p H value in children were observed. Results After nasal continuous positive airway pressure ventilation, the levels of Pa O2, post-PCO2, Pa O2/ Fi O2 and p H value of children were better than the positive pressure ventilation before treatment and positive pressure ventilation（P 〈0.05）.Conclusions Nasal continuous positive airway pressure ventilation has good therapeutic effect on severe respiratory disease in children with neonatal hypoxemia. Good ventilation pressure regulation, skin and mucosa protection, prevention of vomiting in children with nursing to ensure the positive significance of continuous positive airway pressure therapy.