超敏CRP和血脂在糖尿病并发大血管病变中的临床应用研究

The Clinical Application of CRP and Lipid in Diabetic Patients with Large Vessel Disease

目的对超敏CRP和血脂在糖尿病并发大血管病诊断中的应用价值进行分析探讨。方法以该院2010年1月—2015年4月收治的70例糖尿病患者作为观察组,以同期在该院进行健康体检的50例志愿者作为对照组,对比两组研究对象的血清Hs-CRP、TG、TC、LDL-C、HDL-C水平。结果并发症组患者的TG、TC及LDL-C明显高于无并发症组及对照组,P<0.05,差异具有统计学意义,无并发症组及对照组患者的TG、TC及LDL-C差异无统计学意义(P>0.05)。3组患者的HDL-C差异无统计学意义(P>0.05)。并发症组的Hs-CRP明显高于无并发症组及对照组,P<0.05,差异具有统计学意义。无并发症组患者的Hs-CRP明显高于对照组,P<0.05,差异有统计学意义。结论 Hs-CRP、TG、TC、LDL-C、HDL-C同糖尿病并发大血管病变有着密切关系,对于该病的诊断及治疗具有十分重要的价值。

Objective To study the diagnosis value of Hs-CRP and blood lipid in diabetes complicated with large vascular disease. Methods Selected 70 cases with diabetes in our hospital from January 2014 to April 2015 as experimental group, and selected 50 healthy volunteers in our hospital at the same period as control group, compared the Hs-CRP, TG, TC, LDL-C and HDL-C of the two groups. Results The TG, TC and LDL-C levels of complication group were much higher than that of non complication group and control group, P〈0.05, the difference had statistical significance. The TG, TC and LDL-C levels between non complication group and control group did not had obvious difference（P〉0.05）. The LDL-C of the three group did not had statistical difference（P〉 0.05）. The Hs-CRP of complication group was higher than that of non complication group and control group, P〈0.05,the difference had statistical significance. The Hs-CRP of non complication group was higher than that of control group, P〈0.05, the difference had statistical significance. Conclnsion The Hs-CRP, TG, TC, LDL-C and HDL-C have imitate relationship with diabetes com- plicated with large vascular disease, and they play important value in the diagnosis and treatment of it.