麦默通旋切术与传统手术处理乳腺肿块的前瞻性研究

The comparison and analysis between the clinical effects of the Mammotome atherectomy and the traditional surgery in the treatment of the breast mass

目的 对比分析乳腺肿块患者采用麦默通旋切术与传统手术治疗效果。方法 自2011年1月-2012年1月期间我院收治的乳腺肿块患者,根据随机数字表法随机分为两组（A组和B组）,A组采用麦默通旋切术治疗,B组采用传统手术治疗。每组患者各210例。共420例入组,每组均210例。对比分析两组手术时间、术中出血量、术后瘢痕大小、术后愈合时间、术后镇痛以及术后并发症发生情况。结果 两组均完整切除乳腺肿块。与B组相比,A组手术时间短、术中出血量少、术后瘢痕小、术后愈合时间短（所有P〈0.05）;并且A组术后镇痛次数也较B组少（P〈0.05）。术后两组并发症发生率的差异无统计学差异。A组随访时间为3个月-32（17.49±3.27）个月,B组随访时间为3个月-29（16.83±3.41）个月,均未发现乳腺内残留病灶。结论 乳腺肿块患者采用麦默通旋切术治疗效果明显优于传统手术,手术时间短、术中出血量少、术后瘢痕小、愈合时间快,并发症少,镇痛效果好,故而临床应用安全可靠,值得进一步推广应用。

Objective To compare and analyze the clinical efficacy of the Mammotome atherectomy and traditional surgery in the treatment of the breast mass. Methods 420 cases of patients with breast mass were diagnosed from Jan 2011 to Jan 2012,.which were randomized into group A（n=210）and group B（n=210）. The patients of group A was treated with Mammotome atherectomy therapy, and those of group B were treated with traditional surgery. The operation time, blood loss,postoperative scar size, incision healing, postoperative analgesia and complications were analyzed and compared between the two groups. Results When compared with group B, the surgical treatment in group A showed excellent results which were as follow, shorter operation time, less intra-operative blood loss, smaller incision scar, shorter healing time, less analgesia use（all P〈0.05）. The follow-up in group A was 3 to 32（an average of 17.49±3.27） months, and was 3 to 29（an average of16.83±3.41） months n B group. The mammary gland residual lesion was not found in both two groups.Conclusion Using the Mammotome atherectomy therapy in the treatment of the breast mass is superior to the traditional surgery, and it is safer and more effective.