1Kaukonen KM, Bailey M, Suzuki S, et al. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012 [ J ]. JAMA, 2014, 311 ( 13 ) : 1308-1316.
2Seymour CW, Rea TD, Kahn JM, et al. Severe sepsis in pre- hospital emergency care : analysis of incidence, care, and outcome [J]. Am J Respir Crit Care Med, 2012, 186(12) :1264-1271.
3Hotchkiss RS, Opal S. lmmunotherapy for sepsis-a new approach against an ancient foe[ J]. N Engl J Med, 2010, 363 ( 1 ) :87-89.
4Gentile LF, Cuenca AG , Efron PA, et al. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care [ J ]. J Trauma Acute Care Surg, 2012, 72(6) :1491-1501.
5Yende S, D'Angelo G, Kellum JA, et al. Inflammatory markers at hospital discharge predict subsequent mortality after pneumonia and sepsis[ J]. Am J Respir Crit Care Med, 2008, 177 ( 11 ) : 1242 -1247.
6Angus DC, van der Poll T. Severe sepsis and septic shock[ J]. N Engl J Med, 2013, 369(9) :840-851.
7Puthucheary ZA, Rawal J, McPhail M, et al. Acute skeletal muscle wasting in critical illness [ J ]. JAMA, 2013, 310 ( 15 ) : 1591-1600.
8Hotchkiss RS, Monneret G, Payen D. Immunosuppression in sepsis : a novel understanding of the disorder and a new therapeutic approach [ J ]. Lancet Infect Dis, 2013, 13 ( 3 ) :260-268.
9Meisel C, Schefold JC, Pschowski R, et al. Granulocyte- macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression : a double-blind, randomized, placebo- controlled multicenter trial [ J ]. Am J Respir Crit Care Med, 2009, 180(7) :640-648.
10Lubbers T, Kox M, de Haan JJ, et al. Continuous administration of enteral lipid- and protein-rich nutrition limits inflammation in a human endotoxemia model[ J]. Crit Care Med, 2013, 41 (5) : 1258-1265.
3Gentile LF, Cuenca AG, Efron PA, et al. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care [J ]. J Trauma Acute Care Surg, 2012, 72 ( 6 ) : 1491 - 1501.
4Wiersinga WJ. Current insights in sepsis: from pathogenesis to new treatment targets [J]. Curr Opin Crit Care, 2011,17(5) : 480-486.
5Angus DC, van der Poll T. Severe sepsis and septic shock[J]. N Engl J Med, 2013,369 (9) : 840-851.
6Vanzant EL, inflammation Lopez CM, Ozrazgat-Baslanti T, et al. Persistent and catabolism syndrome after severe blunt trauma [J]. J Trauma Acute Care Surg, 2014, 76( 1 ) : 21-30.
7Hu D, Ren J, Wang G, et al. Persistent inflammation- immunosuppression catabolism syndrome, a common manifestation of patients with enterocuta [J]. J Trauma Acute Care eous fistula in intensive care Surg, 2014,76(3) :725-729.
8Hotchkiss RS, Opal S. Immunotherapy for sepsis-a new approach against an ancient foe[ J ]. N Engl J Med, 2010,363 ( 1 ) : 87-89.
9Girard K, Raffin TA. The chronically critically ill: to save or let die? [J]. Respir Care, 1985,30(5) :339-347.
10McCubbin HI, Thompson EA, Thompson AI, et al. Culture, ethnicity, and the family: critical factors in childhood chronic illnesses and disabilities[J]. Pediatrics, 1993,91(5 Pt 2):1063- 1070.