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胃增生性息肉的临床、内镜及病理特点分析 被引量:8

Analysis of clinical, endoscopic and pathological characteristics of gastric hyperplastic polyps
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摘要 目的 分析胃增生性息肉的临床、内镜及病理特点.方法 回顾性分析北京大学第三医院2005年1月至2014年10月经胃镜及病理学检查确诊为胃增生性息肉的1 676例患者的资料.结果 胃增生性息肉患者中女性占61.46%(1 030/1 676);≥60岁者占60.50%(1 014/1 676);息肉多分布于胃底及胃体,占65.21%(1 093/1 676);息肉合并异型增生占5.31% (89/1 676),合并肠化生占5.61% (94/1 676);息肉局灶癌变占0.30% (5/1 676).背景胃黏膜中幽门螺杆菌相关胃炎占21.96%(368/1 676),自身免疫性胃炎占14.20%(238/1 676),肠化生占22.61%(379/1 676),异型增生占6.56%(110/1 676),腺癌占0.78%(13/1 676),类癌占0.18%(3/1 676).结论 胃增生性息肉多分布于近端胃,息肉组织可以发生癌变.息肉背景胃黏膜存在癌及癌前病变,内镜检查时应重视息肉背景胃黏膜检查. Objective To investigate the clinical,endoscopic and pathologic characteristics of gastric hyperplastic polyps.Methods A total of 1 676 gastric hyperplastic polyps patients diagnosed by gastroscopy and pathology from January 2005 to October 2014 were enrolled and analyzed retrospectively.Results Among them,1 030 patients (61.46%) were female,1 014 patients (60.50%) aged ≥ 60 years old,1 093 patients (65.21%)polyps distributed in the fundus and body of stomach.And the concurrent conditions included dysplasia in polyps tissue (n =89,5.31%),intestinal metaplasia (n =94,5.61%),focal carcinoma (n =5,0.30%).In the background gastric mucosa included Helicobacter pylori gastritis (n =368,21.96%),autoimmune gastritis (n =238,14.20%),intestinal metaplasia(n =379,22.61%),dysplasia (n =110,6.56%),adenocarcinoma (n =13,0.78%),carcinoid tumor (n =3,0.18%).Conclusions Hyperplastic polyps are mainly distributed in the proximal stomach,and malignant transformation may be detected in hyperplastic polyps.Whereas,both precancerous lesions and malignant transformation are detected in background gastric mucosa.Therefore,the endoscopist should always pay attention to background gastric mucosa.
出处 《中华医学杂志》 CAS CSCD 北大核心 2015年第28期2285-2287,共3页 National Medical Journal of China
关键词 息肉 螺杆菌 幽门 自身免疫性胃炎 背景胃黏膜 Polyps Stomach Helicobacter pylori Autoimmune gastritis Background gastric mucosa
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