中国女性乳腺癌发病死亡和生存状况

Incidence,mortality and survival analysis of breast cancer in China

目的：通过对肿瘤登记数据的分析,了解中国女性乳腺癌的流行现况及生存状态。方法：根据全国肿瘤登记中心的数据资料,评估全国乳腺癌的流行情况,并分析乳腺癌长期变化趋势及生存状况。结果：2011年中国女性乳腺癌发病人数约24.9万,发病率37.86/10万,近10年发病呈上升趋势,年龄调整后上升减缓。每年死亡约6.0万,死亡率9.21/10万,近10年乳腺癌死亡率呈上升趋势,年龄调整后上升幅度减缓。乳腺癌患者的1、3和5年观察生存率分别为90.5%、80.0%和72.7%,5年相对生存率为73.0%（95%CI为0.712~0.749）。结论：乳腺癌是威胁我国妇女健康的主要恶性肿瘤之一,疾病负担依然日益加重,应进一步加强乳腺癌的防治工作。

Objective： Based on cancer registry data, the present work aimed to analyze breast cancer survival and epidemiology in China. Methods： The cancer data was retrieved from the National Central Cancer Registry Database. The new diagnosis situation and the number of deaths due to breast cancers were estimated. The time trend and survival for breast cancer were also analyzed. Results： About249,000 new cases, with a 37.86/100,000 crude incidence rate, of female breast cancer were diagnosed in China in 2011. The crude incidence rate increased over the past ten years, and the trend for age-standardized rate increased gradually. Approximately 60,000 deaths were caused by breast cancer in China in 2011, with a crude mortality rate of 9.21/100,000. The crude mortality for females with breast cancer in China increased over the past several decades; however, after regulation of age-standardized rate, this increasing trend declined. The combined 5year age-standardized relative survival rate was 73.0%（95% CI： 71.2% to 74.9%）, and the 1, 3, and 5 year observed survival rates were 90.5%,80.0%, and 72.7%, respectively. Conclusion： Breast cancer is a major cancer that threatens the people in China. Therefore, the burden of breast cancer is still heavy. The task of cancer treatment remains severe and serious.