黄秋葵水提物抗运动疲劳作用研究

Effect on anti-exercise-fatigue of okra extracts

目的:观察黄秋葵水提物对实验动物的抗疲劳效果。方法:制备黄秋葵全果水提物,测定提取物中功效成分含量,分别以4、8 g/kg体重/d灌胃21 d,通过小鼠跑台力竭实验和负重游泳力竭实验,结合疲劳相关的生化指标的测定,观察黄秋葵水提物的抗疲劳效果。结果:黄秋葵水提物中含多糖101.1 mg/g,总黄酮3.37 g/100 g,总氨基酸42.4 g/100 g,黄秋葵水提物可显著延长小鼠跑台力竭时间(P≤0.01),8 g/kg黄秋葵水提物还可显著延长负重游泳时间(P≤0.01),显著降低疲劳状态下血清尿素氮(BUN)和血清乳酸(LA)含量。结论:黄秋果具有良好的抗疲劳效果。

Objective：Observe the anti-fatigue effect of the water extracts of okra（Abelmoschus esculentus） in mice.Method：Preparation of okra by water extract and measuring the functionality of the extract,and intragastric administration was given the mice with two dosages（4 g/kg,8 g/kg body weight per day） for 21 days.Exhaustive time of treadmill testand weight-loaded swimming test were respectively employed to evaluate the endurance capacity of mice combined with the different biochemical indicators,including blood urea nitrogen（BUN）,blood lactic acid（LA） and hepatic glycogen levels.Result：The content of polysaccharide,flavonoid and total amino acid in okra extract is 101.1 mg/g,3.37 g/100 g and 42.4 g/100 g.The exhaustive treadmill running time was increased significantly（P≤0.01） in okra extracts groups,the swimming time was increased significantly（P≤0.01） in 8 g/Kg okra extracts group,when compared with the model group.BUN and LA were significantly decreased（P ≤ 0.01 and P ≤ 0.001）,while there was no significant difference of hepatic glycogen when compared with normal control group and model group.Conclusion：The study indicates that okra water extracts process an anti-fatigue effectby decreasing the levels of blood urea nitrogen and lactic acid.