石辛含片在下颌第三阻生磨牙拔除术后伤口恢复中的临床疗效观察

The effects of Shixinyatong buccal tablets in patients after the extraction of mandibular third molar

目的:研究石辛含片在下颌第三阻生磨牙拔除术后伤口恢复中的疗效。方法:对拔除下颌第三磨牙患者随机分为3组(n=50)。石辛组患者术后含化石辛含片,0.6 g/次,4次/d;头孢组患者术后口服头孢类抗生素,0.5 g/次,2次/d;对照组患者术后不服用任何药物。观察周期5 d,术后第3天和第5天复查。对术区症状分级计分。用SAS 9.0统计分析。结果:3组患者人口学特征以及手术难易程度组间无统计学差异(P>0.05)。石辛组第5天时症状总积分、主症积分、次症积分、伤口疼痛程度、红肿程度以及口气计分低于对照组(P<0.05)。石辛组与头孢组比较,第3天和第5天症状总积分,主症积分及次症积分无统计学差异(P>0.05)。结论:石辛含片在拔牙术后应用,能够有效防治常见并发症,减少术后抗生素的使用。

Objective： To study the effects of Shixinyatong buccal tablets （SBT） in patients after the extraction of mandibular third molar. Methods： 150 cases of patients were divided into 3 groups（ n = 50）. After tooth extraction the patients in SBT, cephalosporin and control groups were given SBT at 0.6 g, 4 times per day, cepholosporin 0.5 g, 2 times per day and no drug respectively. At the 3rd and 5th day the patients were followed up and their local symptoms were scored. The data were statistically analyzed with SAS 9.0 soft ware. Results： Between SBT and cepholosporin or control group there was no statistical difference in demographic data and impac- tion types of the teeth（ P 〉 0.05 ）. The total symptom integral, primary symptom integral, minor symptoms, wound pain, redness, swelling degree and oral odor in SBT group were lower than those in control group（P 〈 0.05） at the 5th day after tooth extraction. Be- tween SBT group and cephalosporin group there was no significant difference （P 〉 0.05 ） in the total symptom integral, primary symp- tom integral, secondary symptom integral at the 3rd and the 5th day. Conclusion： Shixinyatong buccal tablet is effective in the preven- tion of complications after the extraction of mandibular third molar.