烟雾病合并后循环病变致继发枕叶梗死的相关危险因素分析

Analysis of the risk factors related to occipital lobe infarction induced by Moyamoya disease complicated with posterior circulation lesions

目的探讨烟雾病合并后循环病变患者发生枕叶脑梗死的相关危险因素。方法 2003年5月至2013年5月收治烟雾病患者846例,合并后循环病变的患者258例,其中在后循环病变基础上伴发枕叶梗死107例,采用多因素Logistic回归分析对烟雾病合并后循环病变时发生枕叶脑梗死的相关危险因素进行分析。结果单因素分析结果显示高血压、吸烟史以及左、右侧前循环铃木分期和左、右侧后循环Magikura分级是烟雾病合并后循环病变致枕叶梗死发生的危险因素(P<0.05)。多因素Logistic回归分析显示高血压循环Magikura分级和年龄是其独立危险因素。结论烟雾病合并后循环病变继发枕叶梗死是多因素作用的结果,正确、全面地认识这些因素的作用有助于降低枕叶梗死的发生率。

Objective To explore the risk factors related to occipital lobe infarction induced by Moyamoya disease （MD） complicated with posterior circulation lesions （PCL）. Methods The clinical data of 258 patients with MD complicated with PCL treated in our hospital from May, 2003 to May, 2013, of whom, 107 had occipital lobe infarction ipsilateral to PCL and 151 not, were analyzed retrospectively. The risk factors related to occipital lobe infarction were analyzed by Logistic regression analysis. Results The risk factors related to the ipsilateral occipital infarction were hypertension, high Magikura stage of posterior circulation and old age in orlder of dangerous nature in the patients with MD complicated with PCL. Conclusions The occipital infarction is related to the multiple factors including hypertension, high Magikura stage and old age and a good understanding of the risk factors is helpful to the decreasing the incidence of occipital infarction in the patients with MD complicated with PCL.