脑动静脉畸形栓塞术后颅内出血影响因素的多元回归分析

Risk factors of hemorrhage after endovascular therapy of cerebral arteriovenous malformations

目的 分析脑动静脉畸形栓塞术后颅内出血的相关影响因素。方法 选取315例脑动静脉畸形患者（c AVM）作为研究对象,运用多元回归分析对患者的性别、年龄、出血史、栓塞体积、高血压病史等脑动静脉畸形出血的多种影响因素进行分析。结果单次栓塞体积≥36.5%的OR=2.184,95%CI为1.117~4.269,（P=0.022,〈0.05）,既往高血压病史的OR=2.184,95%CI为1.041~4.581,（P=0.039,〈0.05）,二者是脑动静脉畸形栓塞术后颅内出血的主要危险因素。结论 血管介入治疗脑动静脉畸形最严重的并发症是脑动静脉畸形,单次栓塞体积≥36.5%和既往高血压病史可增加脑动静脉畸形栓塞术后颅内出血的危险性。

Objective To explore the related risk factors of hemorrhage after endovascular therapy of cerebral arteriovenous malforma- lions. Methods Totally 315 patients with cerebral arteriovenous malformations（cAVM） were selected to be as the research subjects, multiple regression analysis was used to analyze the related risk factors of cAVM,such as patient＇s gender, age, history of bleeding, embolism volume, and hypertension history. Results A partial AVM reductiun of≥36.5% in one sessiun（OR =2. 184,95%CI 1. 117 ~4. 269,P =0.022）,and hypertension history（ OR =2. 184,95% CI 1. 041 - 4. 581, P = 0. 039 ） were the main risk factors of hemorrhage ＇after endovaseular therapy of cAVM. Conclusion lntracranial hemorrhage is one of the mos! serious complications ＇after the cerebral arteriovenous malformation embolization, a partial AVM reduction of 〉 36.5% in one session and hypertension history, have a tendeney of increasing hemorrhage after endovascular therapy.