冷冻胚胎移植周期中黄体支持的研究现状

Luteal Phase Support in Cycles of Frozen-thawed Embryo Transfer

在冷冻胚胎移植(FET)周期中主要采用自然周期(natural cycle)和激素替代周期(hormone replace treatment cycle)进行内膜准备。激素替代周期行FET后常规进行黄体支持已无异议。但在自然周期中进行FET是否需要进行黄体支持,以及在自然周期及激素替代周期中进行FET的最适黄体支持药物的选择及药物的剂型、剂量等方面,学术界并未达成共识,尤其是黄体支持方案对FET的结局影响结论不同。综述近年FET中的黄体支持研究,旨在为今后临床上合理选择黄体支持方案提供帮助。

In the cycle of frozen-thawed embryo transfer（FET）, natural cycle and hormone replacement cycle are the most commonly used for endometrial preparation. There is no disagreement on the necessity of luteal phase support in hormone replacement cycles. However, there are still no consensus on the necessity of luteal phase support in natural cycles, as well as the suitable drugs, dosage form and dose in natural cycles and hormone replacement cycles. There was not a conclusion on the effects of luteal phase support on the outcomes of FET.This review stated the luteal phase support in the cycles of FET, so as to improve clinical application of the luteal phase support.