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微小核糖核酸-208与心血管疾病关系研究进展 被引量：3

Research Progress of Relationship Between miRNA-208 and Cardiovascular Disease
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摘要 微小核糖核酸是一类长21~25个核苷酸的高保守性的非编码小分子RNA,主要通过与靶基因真核mRNA的3’非翻译区结合而调控基因的表达。近年来研究发现循环血微小核糖核酸在心血管疾病中的含量会发生变化,现就心肌特异性的微小核糖核酸-208在心血管疾病的研究进展做一综述。 MicroRNA（ miRNA） is a class of highly conserved non coding small molecule RNA,which is about 21 - 25 nucleotides,and regulates the expression of genes by combining 3＇-UTR mRNA region. In recent years,it has been found that the contents of circulating blood miRNAs in cardiovascular diseases will change. This article reviews the progress of miRNA-208 in the research of cardiovascular disease.
作者 刘新秀 阮长武 葛智儒
机构地区 上海第二军医大学附属公利医院心内科 宁夏医科大学研究生院
出处 《心血管病学进展》 CAS 2015年第4期368-371,共4页 Advances in Cardiovascular Diseases
基金 上海市浦东新区科技发展基金创新资金(PKJ2011-Y22)
关键词 微小核糖核酸-208 心血管疾病 研究进展 miRNA-208 cardiovascular disease research progress
分类号 R54 [医药卫生—心血管疾病]
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参考文献24

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二级参考文献36

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心血管病学进展
2015年 第4期

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