期刊文献+

咪达唑仑联合氯胺酮浅镇静技术对婴幼儿法洛四联征术后的影响 被引量:1

下载PDF
导出
摘要 目的:探讨咪达唑仑联合氯胺酮对法洛四联征术后患儿的镇痛镇静效果及预后影响。方法:60例法洛四联征根治术后患儿,随机分为咪达唑仑组(A组)30例、咪达唑仑+氯胺酮组(B组)30例;A组咪达唑仑0.1 mg·kg-1静脉注射负荷量镇静诱导,起效后微量泵持续静注。B组实施浅镇静策略,在使用咪达唑仑的基础上,加用氯胺酮,Ramsay评分2~3分,结合脑电双频指数监测仪镇静评估。结果:B组在机械通气24 h后CVP明显降低(P〈0.05);在机械通气过程中,B组咪达唑仑用量明显低于A组(P〈0.05);B组机械通气时间明显短于A组(P〈0.05)。结论:咪达唑仑联合氯胺酮镇静镇痛能在术后24 h内明显改善心功能;能减少机械通气中咪达唑仑用量,能减少术后机械通气时间。
出处 《赣南医学院学报》 2015年第3期383-384,387,共3页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
基金 赣州市科技局课题(编号:GZ2014ZSF015)
  • 相关文献

参考文献8

二级参考文献32

  • 1安友仲,邱海波,黄青青,康焰,管向东.中国重症加强治疗病房患者镇痛和镇静治疗指导意见(2006)[J].中华外科杂志,2006,44(17):1158-1166. 被引量:243
  • 2Kennedy RM, Luhmann JD, Luhmann SJ.Emergency department management of pain and anxiety related to orthopedic fracture care: a guide to analgesic techniques and procedural sedation in children[J]. Paediatr Drugs, 2004,6 : 11.
  • 3Bleiberg AH,Salvaggio CA,Roy LC ,et al.Low-dose ketamine. Efficacy in pediatric sedation[J].Pediatr Emerg Care,2007,23:158.
  • 4Morton NS. Ketamine for procedural sedation and analgesia in pediatric emergency medicine: a UK perspective[J].Pediatr Anesth, 2008,18:25.
  • 5Elia N,Tramer MR. Ketamine and postoperative pain a quantita rive systematic review of randomized trials[J].Pain, 2005,113:61.
  • 6Grande LA,O'Donnell BR, Fitzgibbon DR et al. Ultra-low dose ketamine and memantine treatment for pain in an opiodtolerant oncology patient[J].Anesth Analg, 2008,107 : 1380.
  • 7Hocking G, Cousins MJ.Ketamine in chronic pain management: an evidence-based review[J].Anesth Analg,2003,97:1730.
  • 8Tucker A,Kim Y,Nadeson R,et al.Investigation of potentiation of analgesic effects of fentanyl by ketamine in humans: a double blinded, randomized, placebo controlled, crossover study of experimental pain[J].BMC Anesthesiol, 2005,5 : 2.
  • 9Tsui BCH,Davies D, Desai S, et al.Intravenous ketamine infusion asan adjuvant to morphine in a 2-year-old with severe cancer pain from metastatic neuroblastoma[J].J Pediatr Hematol 0ncol,2004, 26 : 678.
  • 10Tsui BCH,Wagner A, Mahood J, et al.Adjunct continuous ketamine infusion for postoperative pain l-lief following posterior spinal instrumentation for correction of scoliosis:a case report[J].Pediatr Anesth,2007,17:383.

共引文献61

同被引文献5

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部