结肠癌术前营养风险特点及对临床结局的影响分析

Analysis on the Characteristics of Nutrition Risk and its Impact on Clinical Outcomes of Patients with Colon Cancer

目的通过对结肠癌患者进行术前营养风险分析,探讨营养状况对临床结局的影响。方法选取2010年10月至2014年9月我院收治的结肠癌患者92例,根据NRS-2002评分标准将患者分为有营养风险组(NRS-2002≥3分,50例)和无营养风险组(NRS-2002<3分,42例)。比较两组患者的术后并发症发生率、切口愈合时间、住院时间和完成化疗次数等情况。结果有营养风险组和无营养风险组的术后并发症发生率、切口愈合时间、住院时间和接受化疗次数相比差异显著,具有统计学意义(P<0.05)。结论结肠癌术前有营养风险的患者特点是男性比例高于女性,肿瘤多位于右侧且分期多为Ⅲ、Ⅳ期,患者平均年龄也较高,而且此类患者术后并发症发生率、切口愈合时间和住院时间均高于无营养风险患者,接受化疗次数也更少。

Objective To investigate the impact of nutritional status on clinical outcomes by analyzing the preoperative nutritional risk of patients with colon cancer. Methods 92 cases of patients with colon cancer admitted to our hospital from October 2010 to September2014 were selected and divided into nutritional risk group（NRS-2002 ≥3 points, 50 cases） and non-nutritional risk group（NRS-2002〈3point, 42 cases）. The incidence of postoperative complications, wound healing time, hospitalization time and times of completing chemotherapy were compared between two groups. Results The incidence of postoperative complications, wound healing time,hospitalization time and times of completing chemotherapy between two groups had statistical difference（P〈0.05）. Conclusions The features of colon cancer patients with nutritional risk are that the male proportion is higher than female proportion, and the tumor mostly locate in right side and the clinical stage tends to be Ⅲ, Ⅳ stage, the average age of those patients is also high, the incidence of postoperative complications, wound healing time and hospitalization time of colon cancer patients with nutritional risk are higher than those of patients without nutritional risk, with less chemotherapy times.