血清C反应蛋白和前白蛋白在早期诊断晚发性早产儿败血症的临床应用

Clinical Application of Serum C Reactive Protein and Prealbumin in Early Diagnosis of Late-Onset Septicemia in Premature Infants

目的分析血清C反应蛋白(CRP)和前白蛋白(PA)二者在早期诊断晚发性早产儿败血症的临床应用。方法选取2013年1月至2014年9月我院收治的40例晚发性早产儿败血症患儿为研究组,另选取同期收治的生活能力低下的40例早产儿为对照组。检测两组患儿入院和出院时的CRP和PA的水平。结果组内比较,两组患儿出院时的CRP水平均显著低于入院时,PA水平均显著高于入院时(P<0.05);组间比较,研究组患儿入院时的CRP水平显著高于对照组,PA水平显著低于对照组(P<0.05);两组出院时CRP水平和PA水平相比差异不显著(P>0.05)。结论 CRP和PA二者联合在早期诊断晚发性早产儿败血症中具有较高的临床应用价值,值得推广。

Objective To analyze the clinical application of serum C reactive protein（CRP） and prealbumin（PA） in early diagnosis of late-onset septicemia in premature infants. Methods 40 cases of premature infants with late-onset septicemia admitted to our hospital from January 2013 to September 2014 were set as study group, 40 cases of premature infants with low viability in same period were set as control group. The levels of CRP and PA of infants were detected on admission and discharge. Results The CRP level of two groups on discharge was lower than that on admission, the PA level of two groups on discharge was higher than that on admission（P〈0.05）; the CRP level of study group on admission was higher than that of control group, the PA level was lower than that of control group（P〈0.05）; the levels of CRP and PA of two groups on discharge had no statistical difference（P〉0.05）. Conclusions The combination of CRP and PA has high clinical application value in early diagnosis of late-onset septicemia in premature infants, which is worthy of promotion.