抗抑郁治疗对脑卒中后康复效果的影响分析

Effect of Antidepressant Therapy on Rehabilitation of Stroke

目的观察脑卒中患者实施抗抑郁治疗对其康复效果的影响与意义。方法选取2011年5月至2014年8月我院收治的脑卒中患者116例,随机分为观察组与对照组各58例,对照组实施常规药物及物理治疗,观察组在此基础上使用盐酸氟西汀胶囊进行抗抑郁治疗,对比观察两组治疗前后的神经功能情况及抑郁程度,评估患者的康复效果。结果两组患者在治疗前各指标基线水平无明显差异(P>0.05),治疗后SSS水平明显降低,HAMD水平显著升高,差异有统计学意义(P<0.05);且观察组治疗后HAMD、SSS水平均明显低于对照组,差异有统计学意义(P<0.05)。结论脑卒中患者常会并发卒中后抑郁,对脑卒中患者实施抗抑郁治疗,能够有效缓解其卒中后抑郁程度,同时对其神经功能缺损的恢复有着积极的促进意义,可以有效改善患者康复效果,具有理想的临床意义与推广价值。

Objective To observe the influence and significance of antidepressant therapy on rehabilitation of patients with stroke.Methods 116 patients with stroke treated in our hospital from May 2011 to August 2014 were randomly divided into two groups, with 58 cases in each group. The control group was treated with routine drugs and physical therapy, the observation group was given fluoxetine hydrochloride capsules for antidepressant treatment on this basis. The neurological function and degree of depression were observed and compared between two groups, the effect of rehabilitation were evaluated. Results Before the treatment, the SSS level and HAMD level of two groups had no statistical difference（P〉0.05）. After the treatment, the SSS level of two groups was decreased, the HAMD level was increased, with statistical difference（P〈0.05）; the SSS level and HAMD level of observation group were significantly lower than those of control group, with statistical difference（P〈0.05）. Conclusions Patients with stroke often associate with cerebral apoplexy depression. The antidepressant therapy on these patients can effectively relieve the degree of post-stroke depression and improve the rehabilitation effect,which also has positive significance on the recovery of neurological function, and has clinical significance and promotional value.