肝硬化患者脾切除术后门静脉血栓形成的危险因素

Risk factors for portal vein thrombosis following splenectomy in patients with liver cirrhosis

门静脉血栓(PVT)发生在部分肝硬化门静脉高压症的患者中并进一步加剧门静脉压力。诱发PVT形成的风险因素尚未明确。但已经注意到脾切除术可能使PVT形成的风险增加;更严重的是如果没有及时诊断和治疗,PVT可能会进展为脾切除术后危及患者生命的一种并发症。分析了脾切除术后PVT形成的危险因素,指出肝硬化患者脾切除术是PVT后天形成的主要原因。

Portal vein thrombosis（ PVT） develops in some patients with liver cirrhosis and may aggravate portal hypertension. The risk factors for PVT have not yet been completely clarified. Splenectomy might increase the risk of developing PVT,which may progress to a life-threatening complication after splenectomy if not diagnosed promptly and treated properly. In this review,we discuss the recent findings concerning the risk factors for PVT after splenectomy. It is pointed out that splenectomy is the major cause of PVT developed in patients with liver cirrhosis.