桑叶中1-脱氧野尻霉素(DNJ)研究进展

Progress on 1-Deoxynojirimycin(DNJ) in Mulberry Leaf

桑叶是1-脱氧野尻霉素(1-deoxynojirimycin,DNJ)最主要的植物来源。作为桑叶中多羟基生物碱的一种特征性成分——糖苷酶抑制剂,广受国内外学者的关注。该研究对DNJ的含量、得率变化的影响因素及功能性药理作用等进行疏理,同时展望了相关研究与应用前景。

Mulberry leaf is the main plant sources of 1-Deoxynojirimycin（ DNJ）. As a characteristic composition-glucosidase inhibitors of polyhydroxy alkaloids in mulberry leaf,DNJ received a wide attention of scholars at home and abroad. This paper reviews the content and yield change influencing factors and functional pharmacological effects of DNJ,and forecasts relevant research and application prospect.