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微量肝素治疗胎粪吸入综合征临床研究 被引量:2

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摘要 目的:探讨微量肝素治疗胎粪吸入综合征的临床效果。方法:选取我院新生儿科治疗的80例胎粪吸入综合征新生儿作为研究对象,随机将其分为观察组和对照组,每组40例。对照组患儿只采取基础治疗,观察组在对照组的基础上应用小剂量肝素进行治疗,连续使用2 d,比较两组患儿在治疗前后的血小板((platelet,PLT)、活化部分凝血活酶时间(activated partial thromboplastin time,APTT)、凝血酶原时间(prothrombin time,PT)、纤维蛋白原、D-二聚体(D-dimer)值、C反应蛋白(C-reactionprotein,CRP)、肌酸激酶同工酶(creatinine kinase MB isoenzyme,CK-MB),并进行统计分析。结果:观察组患儿的各项指标均优于对照组,两者比较差异具有统计学意义(P<0.05)。结论:针对胎粪吸入综合征患者,采取早期微剂量(6 U/kg)肝素治疗,能改善新生儿凝血功能障碍、减少肺出血、DIC、颅内出血的发生,降低心、脑、肺缺血再灌注损伤等方面效果显著,提高了抢救成功率。
出处 《包头医学院学报》 CAS 2015年第7期48-49,共2页 Journal of Baotou Medical College
基金 湛江市科技攻关计划项目(2012C3104069)
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