植物多糖对免疫性肝损伤的药理作用研究进展

Advances in Study of Immunological Liver Injury Pharmacological Effects of Plant Polysaccharides

从介绍免疫性肝损伤的病因病机、治疗措施入手,阐述植物多糖对免疫性肝损伤的药理作用在于调节ALT和AST水平,降低TNF-α、IL-1等炎症介质,影响肝中NO和NOS(一氧化氮合酶)含量及调节外周血淋巴细胞亚群等方面,认为植物多糖是治疗免疫性肝损伤的创新药物,具有很好的开发价值和临床应用前景。

Based on the etiology and pathogenesis and treatment of immunological liver injury, the pharmacological action of Plant polysaccharides on immunological liver injury was expounded, including regulation of the level of ALT and AST, reducing TNF-α and IL-6, influence on NO and NOS （Nitric oxide synthase）, and lymphocyte subsets in peripheral blood lymphocytes. Plant polysaccharide is an innovative drug for the treatment of immune liver injury, which has a good development value and clinical application prospect.