慢性阻塞性肺疾病早期筛查方法及临床意义

Feasible methods and the clinical meaning of early detection for chronic obstructive pulmonary disease

目的探讨COPD早期筛查的相关可行性方法及临床意义以提高COPD临床诊断率。方法通过查阅相关文献，分析归纳总结目前l临床上对COPD早期筛查的可行性办法。结果临床上仍然以肺功能检查作为COPD的主要诊断方法，但临床实践中并不能完全依赖肺功能检查，应结合其他替代指标，如胸部HRCT、生物指标、COPD筛查问卷、呼气峰流速及6分钟步行试验等，以提高临床诊断率。结论COPD是严重影响患者身心健康的慢性疾病之一，有效运用筛查方法对患者进行早期诊断，早期治疗具有深刻的临床煮义．

Objective To explore the feasible methods and the clinical meaning of early detection for chronic obstructive pulmonary disease （COPD） in order to improve clinical diagnostic rate. Methods Related literatures were reviewed to analyze and summarize the feasible way of early detection for COPD. Results Pulmonary function test is still the main diagnostic method for COPD. But it should not be completely relied on to make a diagnosis in clinical practice. Other surrogate index, such as the high resolution computed tomography （HRCT）, biological indicators, symptom based questionnaire for identifying COPD,peak expiratory flow （PEF） and the six-minute walk test should be used to improve the diagnostic rate. Conclusions COPD is a chronic disease which affects seriously on patients＇ health and quality of life. Effective use of these screening methods has great clinical significance in early detection and treatment of COPD.