降钙素原联合病原体检测在下呼吸道感染诊断中的应用价值

Application value of procalcitonin combining with pathogen detection in the diagnosis of lower respiratory tract infection

目的探讨降钙素原（PCT）联合病原体检测在下呼吸道感染诊断中的应用价值。方法随机选取2013年1月-2014年9月在本院接受治疗的80例呼吸道感染患者作为研究对象,按照入院顺序将其分为观察组（细菌感染）和对照组（非细菌感染）,每组40例。对两组患者进行血清PCT水平检测及呼吸道Ig M九联检血清抗体的检测,观察并分析两组的阳性率、血清PCT水平、Ig M抗体和痰培养结果。结果观察组患者的阳性率和PCT水平分别为90%和（5.09±0.78）ng/ml,显著高于对照组,差异有统计学意义（P〈0.05）。观察组患者痰培养阳性率为30%,显著高于对照组的0%,而呼吸道Ig M抗体阳性率仅为5%,显著低于对照组,两组差异有统计学意义（P〈0.05）。结论对下呼吸道感染患者采用PCT联合呼吸道Ig M九联检,可提高临床诊断率,并对药物的选择治疗有着重要的指导意义,值得临床推广应用。

Objective To study the application value of procalcitonin （PCT） combining with pathogen detection in the diagnosis of lower respiratory tract infection. Methods 80 patients with respiratory tract infections from January 2013 to September 2014 into our hospital were selected as research objects.According to the sequence of admission into hospital,they were evenly divided into observation group （bacterial infection） and control group （non-bacterial infection）,40 cases in each group.Two groups were provided with serum PCT density detection and serum antibody of IgM 9-joint detection in respiratory tract by electrochemistry.The positive rate,serum PCT level,IgM antibody and sputum culture in two groups was observed and analyzed. Results The positive rate and the PCT level in the observation group respec- tively was 90%,（5.09±0.78） ng/ml,which were significantly higher than those in the control group,the difference was sig- nificant （P〈0.05）.The positive rate of sputum culture in the observation group was 30%,which was significantly higher than 0% in control group.The positive rate of IgM antibody in respiratory tract only was 5%,which was lower than that of control group,the difference was significant （P〈0.05）. Conclusion For patients with lower respiratory tract infections, application of PCT combining with IgM 9-joint detection in respiratory tract can improve the clinical diagnostic rate and have important guiding significance on medication selection,which is worthy of expansion in clinic.