补肾益肝活血方治疗早期缺血性股骨头坏死55例

Fifty-Five Cases of Early Ischemic Necrosis of the Femoral Head Treated with Prescription for Tonifying Kidney-Liver and Promoting Blood Circulation

目的:观察补肾益肝活血方加减治疗早期缺血性股骨头坏死的临床效果。方法:选取早期缺血性股骨头坏死患者110例,随机分成对照组和观察组,每组55例。对照组予西医非手术治疗,观察组在对照组治疗的基础上加用补肾益肝活血方治疗。结果:对照组优良率63.63%,观察组优良率74.55%,观察组优于对照组(P<0.05);观察组骨髓水肿程度优于对照组(P<0.05);观察组治疗后疼痛程度、关节畸形、关节活动范围、关节功能评分均优于对照组(P<0.05);观察组治疗后脂联素、TNF-α、NO、CRP水平均优于对照组(P<0.05)。结论:补肾益肝活血方能改善早期缺血性股骨头坏死临床症状,延缓病情进展,提高临床效果。

Objective： To observe the clinical curative effect of modified prescription for tonifying kidney-liver and promoting blood circulation for early ischemic necrosis of the femoral head. Methods： One hundred and ten patients with early ischemic necrosis of the femoral head were randomly divided into the control group and the observation group,with 55 cases in each group. The patients in the control group were given Western non-operative treatment,while the ones in the observation group were added modified prescription for tonifying kidney-liver and promoting blood circulation based on the treatment of the control group. Results： The excellence rate of the control group was 63. 63%,while that of the observation group was 74. 55%; The observation group was better than the control group（ P 〈0. 05）. Bone marrow edema of the observation group was better than that of the control group（ P 〈0.05）. After the treatment,pain level,joint deformity,range of motion,joint function score of the observation group were all better than those of the control group（ P 〈0. 05）. After the treatment,adiponectin; TNF-α,NO and CRP the observation group were all better than those of the control group（ P 〈0. 05）. Conclusion： Prescription for tonifying kidney-liver and promoting blood circulation can improve the symptoms of early ischemic necrosis of the femoral head,delay disease development and enhancing the clinical curative effect.