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目标导向液体管理对食管癌根治术血流动力学影响的观察 被引量:4

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摘要 目的:观察术中目标导向液体管理对食管癌根治术患者血流动力学的影响。方法:选择择期行食管癌根治术60例,随机分为以胸腔内血容积指数(ITBVI)为导向的目标导向液体治疗组(观察组)和常规液体治疗组(对照组)各30例;观察组术中以ITBVI值800-1000进行指导补液,对照组则根据临床传统“4—2—1”法则指导补液。采用脉搏指示连续心排血量(PiCCO)监护仪,记录麻醉诱导前(T0)、麻醉诱导后5min(T1)、双肺通气15min(T2)、单肺通气15min(T3)、肺复张后双肺通气15min(T4)和术毕(T5)患者心率(HR)、平均动脉压(MAP)、心脏指数(CI)等指标变化,同时记录患者输液总量、胶体液量、失血量、尿量、手术时间,以及胃肠道首次排气、排便、开始进食等功能恢复时间及住院时间,记录患者术后心肺系统并发症发生情况。结果:观察组T4、T5时点HR显著慢于对照组(P〈0.05);观察组T5时点MAP显著高于对照组(P〈0.05);观察组T4、T5时点CI显著高于对照组(P〈0.05)。观察组术中输注液体总量(2035.6±265.8)ml,显著少于对照组的(2186.8±234.5)ml(P〈0.05);观察组输注胶体液量(918.3±148.6)m1,显著多于对照组的(786.4±166.4)ml(P〈0.05)。两组手术时间、失血量及尿量比较,均差异不显著(P〉0.05)。观察组患者术后首次排气(2.8±0.4)天、首次排便(3.5±0.8)天、开始进食时间(6.4±1.1)天,均显著短于对照组的(3.2±0.5)天、(4.0±0.6)天和(7.1±0.8)天(P〈0.05);两组住院时间比较,差异不显著(P〉0.05)。(4)两组患者术后均未出现心律失常、心肌缺血、心力衰竭及肺部感染、低氧血症、肺水肿、呼吸衰竭等心肺系统严重并发症。结论:术中目标导向液体管理能够有效维持食管癌根治术患者血流动力学稳定,加速胃肠道功能恢复,有助于术后康复。
出处 《人民军医》 2015年第8期892-894,共3页 People's Military Surgeon
基金 承德市科学技术研究与发展计划(20142051)
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参考文献14

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