功能性消化不良餐后不适综合征患者52例胃中液体食物分布特点

Characteristics of liquid food distribution in the stomach of 52 patients with postprandial distress syndrome- predominated functional dyspepsia

目的探讨功能性消化不良（FD）餐后不适综合征（PDS）患者液体食物胃中分布情况，了解其胃动力障碍发病机制。方法应用超声诊断仪对52例PDS患者和18名健康志愿者进行胃排空检查，在空腹，最大饱腹感，餐后30、60、90和120rain分别计算近端胃与远端胃面积和容积，近端胃与远端胃面积比率和容积比率，近端胃和远端胃排空率。统计学处理采用t检验、卡方检验。结果空腹、餐后120min时，PDs组近端胃容积分别为（9．06±7．88）和（24．72±24．02）cm3，健康对照组分别为（5．96±2．13）和（19．48±12．32）cm3，差异均有统计学意义（t=-1．637、-0．875，P均〈0．05）。在最大饱腹感时，PDS组近端胃与远端胃面积比率为1．63±0．42，健康对照组为2．33±0．63，差异有统计学意义（t=5．044，P〈0．05）。在空腹时，PDS组近端胃与远端胃容积比率为0．60±0．38，健康对照组为0．46±0．19，而在最大饱腹感时，PDS组为0．91±0．27，健康对照组为1．30±0．48，差异有统计意义（t=-1．505、3．970，P均〈0．05）。在餐后30、90min时，PDS组近端胃排空率分别为（28．10±25．03）％和（68．80±16．14）％，健康对照组分别为（34．97±14．41）％和（75．86±9．86）％，差异有统计学意义（t=1．087、1．718，P〈0．05）；两组远端胃排空率差异均无统计学意义（P均〉0．05）。结论PDS患者液体食物分布在最大饱腹感时远端胃容积大于近端胃容积，这可能是导致其近端胃排空率下降的原因，近端胃对PDS患者胃动力影响较大。

Objective To explore the distribution of the liquid food in the stomach of patients with postprandial distress syndrome （PDS）-predominated functional dyspepsia （FD） and the mechanism of its gastric dynamic dysfunction. Methods Fifty-two patients with PDS and 18 healthy volunteers underwent gastric emptying examination with ultrasound scanner provided. The proximal and distal gastric area and volume, area and volume ratio of proximal and distal gastric as well as emptying rate of proximal and distal gastric were calculated at fasting, maximum satiety, 30 min, 60 rain, 90 rain and 120 min after meal. Student＇s t test and χ2 test were performed for statistical analysis. Results Proximal gastric volume of PDS group at the time of fasting and 120 min after meal were （9.06±7.88） and （24.72±24.02） cm3 , which were larger than those of healthy control group （（5. 96±2. 13） cm3, （19. 48±12. 32） cm3）, and the differences were statistically significant （t=-1. 637 and -0. 875 ,both P〈0.05）. Ratio of proximal and distal gastric area at maximum satiety in PDS group was 1.63±0.42 and that in healthy control group was 2.33±0.63, and the difference was statistically significant （t= 5. 044, P〈0.05）. Ratio of proximal anddistal gastric volume in PDS group and healthy group at fasting was 0. 60 - 0. 38 and 0. 46 ± 0. 19, respectively, that at maximum satiety was in PDS group and healthy group 0.91 ±0.27, 1.30 ± 0.48, respectively, and the differences were statistically significant （t=- 1. 505 and 3. 970, both P〈0.05）. The emptying rates of proximal stomach of PDS group at 30 min and 90 min postprandial were （28.10± 25.03）% and （68.80±16.14）%, respectively, those of healthy control group were （34. 97±14.41）% and （75.86±9.86） %, and the differences were statistically significant （t = 1. 087 and 1. 718, both P〈 0. 05）. There was no statistically significant difference in emptying rate of distal stomach between two groups （all P〉0. 05）. Conelusions The volume of distal stomach was larger than that of proximal stomach in PDS patients at maximum satiety in liquid food distribution, which may be the cause of decreasing emptying rate of proximal stomach. And proximal stomach dominated gastric motility in PDS patients.