腹主动脉瘤动物模型的建立及发病机制的研究进展

Progress of the methods for inducing animal model of abdominal aortic aneurysm and researches on the etiology

本文报导了腹主动脉瘤动物模型的建立方法和发病机制。腹主动脉瘤的形成是由遗传学和生物化学等多种因素相互影响和共同作用的结果。多种腹主动脉瘤动物模型的建立方式为研究其病因学的发病机制的等方面提供了可能 ,并对腹主动脉瘤临床治疗、并发症防治 。

This paper reports the methods of inducing animal model of abdominal aortic aneurysm(AAA) and the research on etiology.The formation of AAA is the result of cooperation of multifactors such as genetic and biochemistric facfors.Different animal models of AAA can provide a possibility in researching the etiology and pathogenesis of AAA etc, and useful in judging the therapy and prognosis .