1[1]Drews J. Drug discovery:A historical perspective. Science, 2000,287:1960.
2[2]Terstappen GC, Reggiani A. In silico research in drug discovery.Trends Pharmacol Sci,2001,22(1) :23.
3[3]Robert FS. High - speed biologists search for gold in proteins. Science ,2001,294:2074.
4[4]Eliot M. A physicist - turned - biologist. Science,2001,294:2085.
5[5]Liggett SB. Pharmacogenetic applications of the human genome project. Nat Med,2001,7(3 ) :281.
6[6]Dervieux T, Medard Y, Verpillat P, et al. Possible implication of thiopurine S - methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine. Leukemia. 2001; 15(11): 1706.
7[7]Lauer SJ, Shuster JJ, Mahoney DH, et al. A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high - risk B - precursor acute lymphoblastic leukemia:a Pediatric Oncology Group phase Ⅲ randomized trial. Leukemia,2001; 15(7): 1038.
8[8]Schmiegelow K, Bretton - Meyer U. 6 - mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high - dose methotrexate in children with acute lymphoblastic leukemia. Leukemia,2001; 15(1) :74.