纳洛酮治疗小儿病毒性脑炎的临床疗效分析

Analysis of Clinical Efficacy of Naloxone in Treatment of Children with Viral Encephalitis

目的探讨纳洛酮治疗小儿病毒性脑炎的方法及疗效。方法 2012年1月至2014年1月本院收治的病毒性脑炎患儿70例,随机分为观察组和对照组,每组35例。对照组给予解痉、脱水、降低颅内压、保护脑细胞等常规治疗,观察组在常规治疗的基础上加用盐酸纳洛酮静脉滴注,观察两组患儿心率、血压及意识恢复情况。结果对照组治愈率为57.14%;治疗组治愈率77.14%,治疗组疗效明显高于对照组,差异具有显著性(P<0.05)。结论应用纳洛酮治疗病毒性脑炎起效快、不良反应少、安全性高、作用可靠,值得临床推广应用。

Objective To explore the method and curative effect of naloxone in the treatment of children with viral encephalitis. Methods From January 2012 to January 2014 in the hospital treated 70 cases of viral encephalitis in children, were randomly divided into observation group and control group, 35 cases in each group, control group was given conventional treatment spasm, dehydration, reducing intracranial pressure, protect brain cells, the observation group in the conventional therapy plus naloxone intravenous drip with hydrochloric acid note, observation of blood pressure and heart rate, consciousness recovery of two groups of children. Results In the control group, the cure rate was 57.14%; the cure rate of 77.14%, the efficacy of the treatment group was significantly higher than that in the control group, the difference was significant（P 0.05）. Conclusion The application of naloxone in the treatment of viral encephalitis quick effect, less side effect, high safety, reliable effect, worthy of clinical application.