妊娠期亚临床甲减对妊娠结局的影响分析

The Analysis of Sub-clinical Hypothyroidism during Pregnancy Impact on Pregnancy Outcome

目的探讨妊娠期亚临床甲减对妊娠结局的影响,进一步指导临床。方法选取我院2013年1月至2015年1月收治住院分娩的妊娠期亚临床甲减患者60例,将其作为观察组,与同期随机收治住院分娩的正常健康产妇患者60例,将其作为对照组,对其两组临床资料进行回顾性分析,观察两组患者对妊娠结局的影响。结果观察组患者妊娠期高血压疾病、贫血、早产、胎盘早剥以及胎儿窘迫、低体质量儿发生率明显高于对照组,差异显著,具有统计学意义(P<0.05)。结论妊娠期亚临床甲减能够引发妊娠期并发症,应加强孕早期的筛查,严密监测妊娠期亚临床甲减产妇的情况,对改善妊娠结局具有重要的意义。

Objective To investigate the effects of subclinical hypothyroidism on pregnancy outcome during pregnancy, further guide clinical application. Methods 60 patients with subclinical hypothyroidism during pregnancy were admitted to hospital delivery in our hospital from January 2013 to January 2015, as an observation group. During the same period, 60 patients with maternal health were admitted to hospital delivery, as a control group. Then retrospectively analyzed the clinical data, and observed the effect on pregnancy outcome in both groups. Results The incidence rates of hypertensive disorders in pregnancy, anemia, premature delivery, placental abruption, fetal distress, low birth weight children in the observation group were significantly higher than that of the control group, the difference had statistical significant（P 0.05）. Conclusion The subclinical hypothyroidism during pregnancy can lead to complications during pregnancy. To improve pregnancy outcome, the screening during first trimester of pregnancy should be strengthened, and closely monitor the situation of maternal subclinical hypothyroidism during pregnancy.