海洋石油工业湛江基地职工脑卒中危险因素分析

Analysis of risk factors of stroke among workers in Zhanjiang Base of Offshore Oil Industry

目的：分析海洋石油工业湛江基地职工脑卒中发病的主要危险因素，为制定脑卒中的预防和控制措施提供科学依据。方法对117例脑卒中住院患者（脑卒中组）和117例非脑卒中者（对照组）进行对照研究，利用统一的《健康调查表》，对收集的所有对象的相关资料进行调查，包括性别、年龄、体质量、长期海上工作年限、吸烟史、饮酒情况、血压、糖尿病史、心脏病史、心理压力、胆固醇、三酰甘油、低密度脂蛋白、高密度脂蛋白、同型半胱氨酸等，结合流行病学调查研究方法以及多种统计方法，分析海洋石油工业湛江基地职工脑卒中主要危险因素。结果多因素非条件Logistic回归分析显示，海洋石油工业湛江基地职工脑卒中相关因素OR值及95％CI值分别为：年龄2．052、1．041～5．063，高血压2．108、1．104～5．152，吸烟2．452、1．156～5．607，糖尿病1．053、1．031～3．077，心脏病史1．965、1．105～4．344，体质量指数2．353、1．120～4．675，心理压力大1．854、1．091～7．501，长期海上工作1．974、1．124～4．351，饮酒0．837、0．784～0．996，同型半胱氨酸血症1．221、1．092～3．325，低密度脂蛋白胆固醇1．536、1．105～2．227，高密度脂蛋白胆固醇0．313、0．092～1．025。结论年龄、高血压、吸烟、糖尿病、心脏病史、心理压力、长期海上工作、总胆固醇、三酰甘油、低密度脂蛋白胆固醇、同型半胱氨酸是脑卒中的危险因素，高密度脂蛋白是脑卒中的保护因素，饮酒不是脑卒中的危险因素。

Objective To explore main risk factors associated with stroke among workers in Zhanjiang Base of Offshore Oil Industry , so as to provide scientific evidence for the development of preventive and control measures against stroke .Methods A comparative study was made by using 117 stroke inpatients and the same number of non-stroke patients .By using the same health survey questionnaire , relative medical data , including gender, age, body mass, yeas of service at sea, smoking, alcoholism, blood pressure, diabetes, heart disease, mental stress, cholesterol, triglyceride, low density lipoprotein cholesterol （LDL-C）, high-density lipoprotein cholesterol （ HDL-C ） and homocysteine were collected and analyzed .Multiple-factor unconditional Logistic regression analysis was applied to evaluate major risk factors associated with stroke among workers in Zhanjiang Base of Offshore Oil Industry .Results Multiple-factor unconditional Logistic regression analysis showed that the OR value and 95%CI for age were （2.052, 1.041-5.063）, hypertension （2.108, 1.104-5.152）, smoking （2.452, 1.156 -5.607）, diabetes （1.053, 1.031 -3.077）, heart disease （1.965, 1.105-4.344）, high body mass index （ 2.353, 1.120-4.675）, high mental stress （1.854, 1.091-7.501）, years of service at sea （1.974, 1.124 -4.351）, alcoholism （0.837, 0.784 -0.996）, homocysteine （1.221, 1.092-3.325）, low-density lipoprotein （1.536, 1.105 -2.227） and high-density lipoprotein （0.313,＆nbsp;0.092-1.025）.Conclusions Research results indicated that age , hypertension, smoking, diabetes, heart disease, high mental stress, long years of service at sea, high body mass index, low-density lipoprotein, homocysteine were all risk factors associated with stroke , high-density lipoprotein cholesterol was a protective factor and alcoholism was not a risk factor of stroke .