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Primary intestinal lymphangiectasia with generalized warts 被引量:1

Primary intestinal lymphangiectasia with generalized warts
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摘要 Primary intestinal lymphangiectasia(PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient. Primary intestinal lymphangiectasia(PIL) is a rare protein-losing enteropathy with lymphatic leakage into the small intestine. Dilated lymphatics in the small intestinal wall and mesentery are observed in this disease. Laboratory tests of PIL patients revealed hypoalbuminemia, lymphocytopenia, hypogammaglobulinemia and increased stool α-1 antitrypsin clearance. Cell-mediated immunodeficiency is also present in PIL patients because of loss of lymphocytes. As a result, the patients are vulnerable to chronic viral infection and lymphoma. However, cases of PIL with chronic viral infection, such as human papilloma virus-induced warts, are rarely reported. We report a rare case of PIL with generalized warts in a 36-year-old male patient. PIL was diagnosed by capsule endoscopy and colonoscopic biopsy with histological tissue confirmation. Generalized warts were observed on the head, chest, abdomen, back, anus, and upper and lower extremities, including the hands and feet of the patient.
出处 《World Journal of Gastroenterology》 SCIE CAS 2015年第27期8467-8472,共6页 世界胃肠病学杂志(英文版)
关键词 Protein-losing ENTEROPATHY LYMPHOCYTOPENIA Cell-mediated IMMUNODEFICIENCY PRIMARY intestinallymphangiectasia WARTS Protein-losing enteropathy Lymphocytopenia Cell-mediated immunodeficiency Primary intestinal lymphangiectasia Warts
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  • 1Vignes S, Bellanger J. Primary intestinal lymphangiectasia(Waldmann’s disease). Orphanet J Rare Dis 2008; 3: 5 [PMID:18294365 DOI: 10.1186/1750-1172-3-5].
  • 2Brasitus TA, Bissonnette M. Protein-losing enteropathy. In:Sleisenger MH, Fordtran JS, editors. Gastrointestinal and liverdiseases: pathophysiology, diagnosis and management. 6th ed.Philadelphia: WB Saunders, 1998: 369-375.
  • 3Lynn J, Knight AK, Kamoun M, Levinson AI. A 55-year-old manwith hypogammaglobulinemia, lymphopenia, and unrelentingcutaneous warts. J Allergy Clin Immunol 2004; 114: 409-414[PMID: 15316525 DOI: 10.1016/j.jaci.2004.02.033].
  • 4Hokari R, Kitagawa N, Watanabe C, Komoto S, Kurihara C,Okada Y, Kawaguchi A, Nagao S, Hibi T, Miura S. Changesin regulatory molecules for lymphangiogenesis in intestinallymphangiectasia with enteric protein loss. J GastroenterolHepatol 2008; 23: e88-e95 [PMID: 18005011 DOI: 10.1111/j.1440-1746.2007.05225.x].
  • 5Oh TG, Chung JW, Kim HM, Han SJ, Lee JS, Park JY, SongSY. Primary intestinal lymphangiectasia diagnosed by capsuleendoscopy and double balloon enteroscopy. World J GastrointestEndosc 2011; 3: 235-240 [PMID: 22110841 DOI: 10.4253/wjge.v3.i11.235].
  • 6Nelson DL, Blaese RM, Strober W, Bruce R, Waldmann TA.Constrictive pericarditis, intestinal lymphangiectasia, andreversible immunologic deficiency. J Pediatr 1975; 86: 548-554[PMID: 1127501 DOI: 10.1016/S0022-3476(75)80145-4].
  • 7Wilkinson P, Pinto B, Senior JR. Reversible protein-losingenteropathy with intestinal lymphangiectasia secondary to chronicconstrictive pericarditis. N Engl J Med 1965; 273: 1178-1181[PMID: 5847556 DOI: 10.1056/NEJM196511252732202].
  • 8Broder S, Callihan TR, Jaffe ES, DeVita VT, Strober W, BartterFC, Waldmann TA. Resolution of longstanding protein-losingenteropathy in a patient with intestinal lymphangiectasia aftertreatment for malignant lymphoma. Gastroenterology 1981; 80:166-168 [PMID: 7450403].
  • 9Chew CK, Jarzylo SV, Valberg LS. Idiopathic retroperitonealfibrosis with protein-losing enteropathy and duodenal obstructionsuccessfully treated with corticosteroids. Can Med Assoc J 1966;95: 1183-1188 [PMID: 5921477].
  • 10Fuss IJ, Strober W, Cuccherini BA, Pearlstein GR, Bossuyt X,Brown M, Fleisher TA, Horgan K. Intestinal lymphangiectasia,a disease characterized by selective loss of naive CD45RA+lymphocytes into the gastrointestinal tract. Eur J Immunol 1998;28: 4275-4285 [PMID: 9862365 DOI: 10.1002/(SICI)1521-4141(199812)28].

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