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全膝关节置换术后2次静脉应用氨甲环酸的疗效及安全性

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摘要 目的探讨人工全膝关节置换术(total knee arthroplasty,TKA)后2次静脉应用氨甲环酸的安全性和有效性。方法选取2014年1月至2014年9月郑州大学第一附属医院骨科六病区行全膝关节表面成形术的100例患者,随机分为术后静脉使用2次氨甲环酸组(A组,分别于术毕关口时及术后3 h)及术后静脉使用1次氨甲环酸组(B组,术毕关口时),每组50例。观察两组患者术后引流量、输血率和深静脉血栓(deep venous thrombosis,DVT)发生率。结果 A组患者术后引流量明显较B组小,输血率低,差异均有统计学意义(P<0.05)。A组出现14例DVT,B组为13例,差异无统计学意义(P>0.05)。结论术后2次使用氨甲环酸可有效减少出血量,降低输血率,且不会提高DVT发生率。
作者 刘冠磊 李毅 许建中
机构地区 郑州大学第一附属医院骨科六病区
出处 《河南医学研究》 CAS 2015年第5期49-51,共3页 Henan Medical Research
关键词 膝关节成形术 氨甲环酸 术后出血 输血率 深静脉血栓形成
分类号 R687.4 [医药卫生—骨科学]
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参考文献6

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二级参考文献32

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共引文献35

河南医学研究
2015年 第5期

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