纤维支气管镜支气管肺泡灌洗治疗儿童肺炎支原体感染125例临床观察

Clinical analysis on fiberoptic bronchoscope in treatment of children with mycoplasma pneumonia infection

目的:探讨纤维支气管镜技术对于儿童肺炎支原体感染的临床应用价值。方法:选取肺炎支原体感染儿童215例为观察对象,按治疗方法不同分为观察组和对照组,对照组行支气管冲洗少量液体注入支气管和灌注大量的液体进行支气管肺泡灌洗,观察组行纤维支气管镜下支气管肺泡灌洗,比较两组患儿术后的肺泡灌洗液细胞学成分、临床疗效和肺不张患儿肺复张情况。结果:观察组与对照组回收的支气管肺泡灌洗液分别为(54±17)%和(61±11)%,经比较,差异无统计学意义(P>0.05);回收液细胞成分方面,观察组总细胞数高于对照组,其中以中性粒细胞上升为主(P<0.05);观察组患儿痊愈率及总有效率明显高于对照组(P<0.05);观察组复张率为96.91%,明显大于对照组的84.93%(P<0.05)。结论:纤维支气管镜技术对于儿童肺炎支原体感染有良好疗效,对合并肺不张者,能促进肺复张、改善预后,值得临床推广应用。

Objective To investigate the clinical application value of mycoplasma pneumoniae infection children by fiberoptic bronchoscopy. Method 125 cases mycoplasma pneumoniae infection children treated by the fiberoptic bronchoscope and 90 cases children not treated by bronchoalveolar lavage were chosen as the research objects,they were divided into the observation group and the control group,followed up four week,the alveolar lavage cytology component,clinical curative effect and lung complex situation of the two groups children were compared. Results 215 cases of children with microscope can see lesions bronchial mucosal swelling hyperemia and with many not a sticky secretion. Compared with the control group,the bronchoalveolar lavage fluid cells of the observation group increased,the neutrophil rose to prominent,there was statistically significant difference（ P〈0. 05）. The clinical efficacy of group were also better than that of the control group,the cure rate of was significantly higher than that of the control group（ 80. 80% vs58. 89%,P〈0. 05）. After treatment,the observation group with the complete pulmonary reexpansion rate of 81. 60% is obviously higher than that of control 62. 22%,there was statistically significant difference（ P〈0. 05）. Conclusion The fibre bronchoscope technology for mycoplasma pneumoniae infection children has good effect,it can promote lung recruitment and improve the prognosis,it is worth promoting in clinical practice.