烧伤早期创面细菌学调查及药敏分析

The Bacteriological Investigation and Drug Sensitivity Analysis in Early Burn Wounds

目的:分析烧伤早期创面主要菌群和药物敏感性,指导烧伤临床抗生素的选择和应用。方法:对我科烧伤者(153例)创面分泌物进行菌株分离培养+药敏实验,并分析结果。结果:送检标本检出病原菌120株(78.4%),其中革兰阴性菌74株(61.7%。以铜绿假单胞菌和大肠埃希氏菌为主);革兰阳性菌46株(38.3%。以金黄色葡萄球菌和表皮葡萄球菌为主)。革兰阴性菌对妥布霉素、阿米卡星、庆大霉素、环丙沙星和左旋氧氟沙星较敏感,革兰阳性菌对万古霉素、呋喃妥因、替考拉宁和环丙沙星较敏感。部分病原菌呈多重耐药性。结论:早期烧伤创面仍以革兰阴性菌感染为主,及早进行创面细菌培养和药敏试验有利于合理选用抗生素。

Objective：To analyze the flora and drug sensitivity in early burn wounds,and to guide the selection and application of antibiotics for burn patients.Methods：The secretion of the burn wounds（153 cases）was collected and cultured,and the drug sensitivity was detected. Results：One hundren and twenty pathogenic bacteria（78.4%）were detected. Among them,there were 74 strains of gram negative bacteria（61.7%,mainly including Pseudomonas aeruginosa and Escherichia coli）, and 46 strains of gram positive bacteria（38.3%, mainly including Staphylococcus aureus and Staphylococcus epidermidis）. Gram negative bacteria were sensitivity to tobramycin,amikacin,gentamicin,ciprofloxacin and levofloxacin,while gram positive bacteria were sensitivity to vancomycin,furadantin,teicoplanin and ciprofloxacin. Some of the bacteria were multidrug resistant. Conclusion：The gram negative bacteria are still the primary pathogenic bacteria in early burn wounds. The wound bacterial culture and drug sensitivity test contribute to the choice of antibiotics.