两种时机应用氧气驱动雾化吸入在无创正压通气治疗COPD患者中的疗效观察

To Observe the Therapeutic Effect of Two Kinds of Timing of Application of Oxygen Driven Atomizing Inhalation in the Treatment of COPD Patients With Noninvasive Positive Pressure Ventilation

目的比较两种时机应用氧气驱动雾化吸入在无创正压通气治疗COPD患者中的疗效。方法收集2014年5～12月入住我院呼吸科的慢性阻塞性肺疾病Ⅲ级患者40例：随机分为观察组A（23人）和对照组B（17人）。A组患者在使用无创正压通气治疗的同时氧气雾化吸入药液，B组患者在无创正压通气治疗间歇期间给予氧气雾化吸入药液，观察两组患者疗效、用药依从性。结果与B组相比，A组患者临床疗效、用药依从性均明显提高，P〈0．05。结论氧气雾化吸入同时联合无创正压通气的雾化方式有显著疗效。

Objective To compare the effect of two kinds of application of oxygen driven atomization inhalation in the treatment of COPD with noninvasive positive pressure ventilation （NPPV）. Methods 40 patients with chronic obstructive pulmonary disease grade III admitted to the Department of respiration were chosen in our hospital from May,2014 to December, the patients were randomly divided into observation group A （23 persons） and control group B （17 persons）. Group A used oxygen atomizing inhalation combined with NPPV at the same time, group B conventional application of oxygen atomizing inhalation in the interval of NPPV. To observe the efficacy, Patient compliance, drug distribution depth of two groups. Results Compared with the group B, the clinical efficacy, patient compliance, drug distribution depth were significantly improved in the group A, P〈0.05. Conclusion Oxygen atomizing inhalation combined with NPPV at the same time has a significant effect.