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舍曲林、去氨加压素及利尿剂联用致严重低钠血症1例 被引量:1

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摘要 低钠血症(血清钠〈134 mmol·L^-1),是住院病人中最常见的电解质紊乱。与血钠正常的患者相比,低血钠患者的死亡率明显升高。住院患者中,低钠血症的死亡率为38%,严重低钠血症是死亡的独立预警指标。一些药物如利尿剂、抗抑郁药、抗癫痫药均可导致无症状或症状性低钠血症。除肾脏排钠增多之外,抗利尿激素分泌的增加和肾脏对抗利尿激素反应降低,同样影响血清钠水平。
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2015年第14期1340-1341,共2页 Chinese Journal of Hospital Pharmacy
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