白芍及其化学成分的药理研究进展

Progress of pharmacological research on radix paeoniae alba and its chemical constituents

白芍为毛茛科多年生草本植物芍药的干燥根,性微寒,味苦而酸,入肝、脾经,具有养血敛阴、柔肝止痛、平抑肝阳等功效,临床用于治疗头痛、眩晕、肋痛腹痛、四肢挛痛、月经不调、自汗盗汗等症,也是自身免疫病、肝炎及肝硬化治疗中重要的组方之一。白芍的化学成分主要为单萜及其苷类、三萜类、黄酮、鞣质、多糖、挥发油等。近年来白芍及其化学成分的药理研究已经取得显著进展,作者就其对抗炎、免疫系统、中枢神经系统、心血管系统、消化系统等方面的药理作用进行综述,以期为扩大白芍的临床用药范围和进一步开发提供参考。

Radix paeoniae alba is the dry root of peony which belongs to ranunculaceae perennial herbaceous plant, it shows the slight cool character, bitter and sour in taste, into the collateral channels of liver and spleen, and has the efficiency of nourishing the blood, convergence Yin, acesodyne and stabilizing liver Yang. It is mainly used to treat headache, vertigo, rib pain and celiodynia, limbs spasm pain, irregular menses and sweating, and is an important part of the prescription in the treatment of autoimmune disease, hepatitis and cirrhosis. The main chemical constituents of radix paeoniae alba include monoterpenes and its glycosides, triterpene, flavonoids, tannins, polysaccharides and volatile oil. In recent years, the pharmacological research on radix paeoniae alba and its chemical constituents has gained significant progress, and the author reviews their pharmacological action on anti-inflammatory, immune system, central nervous system, cardiovascular system and digestive system, in order to provide the reference for expanding clinical application and implementing further development of radix paeoniae alba.