肺癌患者血清SOD水平的临床意义

The clinical significance of serum SOD levels in lung cancer patients

目的探讨肺癌患者血清SOD含量的临床价值。方法选择172例初治肺癌患者,均经病理确诊,检测血清SOD含量,观察肺癌临床病理因素与血清SOD含量的关系。结果肺癌患者血清SOD水平与性别无显著相关性(P>0.05),与年龄差异、病理分型存在相关性(P<0.05)。肺癌患者不同临床分期血清SOD水平存在差异(P<0.05),尤其出现远处转移的肺癌患者血清SOD含量显著低于未出现转移患者。结论不同年龄段、不同病理分型以及临床分期肺癌患者血清SOD含量均存在差异,检测患者血清SOD含量结合临床病理因素,对患者的病情评估及预后判断存在潜在的价值。

Objective To study the clinical value of serum SOD content in lung cancer patients.Methods The 172 cases of newly diagnosed lung cancer patients,who were pathologically confirmed,were enrolled in the study. The content of serum SOD in them was detected,the relationship between lung cancer clinicopathological factors and levels of serum SOD were observed. Results There are no significant correlation between gender and levels of serum SOD of patients with lung cancer（ P〉0. 05）. But levels of serum SOD was correlated with age and pathological type（ P〈0. 05）. The level of serum SOD related to clinical stages of lung cancer patients（ P〈0. 05）. Serum SOD content in distant metastases patients was significantly lower than that of no metastases patients. Conclusions The levels of serum SOD was correlated to age,pathological type and clinical stage,serum SOD content detection combine with clinical pathological factors has potential value in assessment the patient＇s condition and prognosis.