OQAS测量散射光和客观视觉质量的可重复性研究

Repeatability of measurement by OQAS for assessment straylight and objective optimal quality

目的 评价OQAS光学质量分析系统对健康人眼、屈光手术术后眼及早期年龄相关性白内障测量客观散射指数（OSI）和MTF截止频率（MTF cut off）、斯特列尔比（SR）等客观视觉质量指标的可重复性.方法 临床病例对照研究.选取2013年3～8月就诊于中国医科大学附属第四医院的50只健康人眼、50只屈光手术（LASIK）术后眼、50只早期年龄相关性白内障眼,使用OQAS测量受试眼的客观散射指数（OSI）、MTF截止频率（MTF cut off）、斯特列尔比（SR）,每项指标测量3次,使用组内相关系数（ICC）及变异系数（CV）为统计学指标评估其可重复性.结果 健康人眼组散射光、MTF cut off及SR测量的ICC及CV值分别为0.921、1.21;0.90、0.2;0.87、0.57;屈光手术术后组散射光、MTF cut off及SR测量的ICC及CV值分别为0.97、1.27;0.90、0.78;0.89、1.91;早期白内障组散射光、MTF cut off及SR测量的ICC及CV值分别为0.96、1.54;0.89、0.71;0.86、2.28.屈光手术术后眼及早期白内障眼的散射光较健康人眼增加,MTF cut off及SR较健康人眼降低,差异均有统计学意义（P＜0.05）.结论 OQAS可以反映客观散射光及视觉质量,在健康人眼、屈光手术术后眼和早期年龄相关性白内障眼中使用重复性均较好。

Objective To assess the repeatability of objective scatter index and other objective optimal quality measured by OQAS doubled-pass system.Methods Fifty healthy subjects,50 post-LASIK eyes and 50 early cataract eyes were recruited in the Eye Hospital of China Medical University from March 2013 to August 2013.The objective scatter index （OSI）,MTF cut off and Strehl ratio （SR） of the eyes were measured by OQAS.Three repeated consecutive measurements were completed by the same examiner.Results The intraclass correlation coefficient （ICC） and coefficient of variation of OSI,MTF cut off and SR in healthy eyes were 0.92,1.21;0.90,0.2;0.87,0.57;The intraclass correlation coefficient （ICC） and coefficient of variation of OSI,MTF cut off and SR in post-LASlK eyes were 0.97,1.27;0.90,0.78;0.89,1.91;The intraclass correlation coefficient （ICC） and coefficient of variation of OSI,MTF cut off and SR in early cataract eyes were 0.96,1.54;0.89,0.71;0.86,2.28.The OSI both in post-LASIK eyes and early cataract eyes were larger than healthy eyes,MTF cut off and SR in post-LASIK eyes and early cataract eyes were smaller than healthy eyes,and there were statistically significant differences.Conclusions OQAS can reflect the objective scatter index and other objective optimal quality.The measurements of OSI,MTF cut off and SR by OQAS doubled-pass system has a high reproducibility.