滇丹参与丹参脂溶性成分指纹图谱的比较研究

Comparison Study on Fingerprints of Liposoluble Components Between Salvia Yunnanensis Roots and Salvia Miltiorrhiza Roots

目的:建立滇丹参脂溶性成分的指纹图谱,并与丹参药材的指纹图谱进行比较。方法:采用高效液相色谱法,建立指纹图谱,并用相似度评价软件对指纹图谱进行评价。结果:滇丹参各样品脂溶性成分的指纹图谱相似度高,与丹参药材脂溶性成分的指纹特征峰组成基本一致,但滇丹参中几个主要脂溶性有效成分的含量均低于丹参。结论:滇丹参与丹参药材的脂溶性成分显示较高的相似性,但其主要成分的含量比例显示明显差异。

To study the fingerprints of liposoluble components in Salvia yunnanensis roots collected from different habi-tats, and compare with the fingerprints of Salvia miltiorrhiza. Methods： The fingerprints were determined by HPLC and the results were analyzed by a similarity evaluation system for chromatographic fingerprints of TCM （ Version 2004 A） . Results：The fingerprints of different samples of Salvia yunnanensis roots showed high similarity. And the characteristic peaks in the fingerprints of the liposoluble components were basically the same as those of Salvia miltiorrhiza, while the contents of several main effective components were lower than those in Salvia miltiorrhiza. Conclusion： The liposoluble components in Salvia yunnanensis roots show relatively high similarity with those in Salvia miltiorrhiza, however, there are obvious differences in the contents of the main constituents.