鼻用纤维素粉末治疗变应性鼻炎的临床疗效分析

Clinical efficacy of nasal cellulose powder for the treatment of allergic rhinitis

目的:探讨鼻用纤维素粉末治疗变应性鼻炎(AR)的临床疗效。方法:36例AR患者随机分成对照组和试验组,每组18例。对照组使用生理性海水喷鼻,试验组鼻腔局部使用鼻用纤维性粉末,分别于用药后14、28d评价患者主观症状和客观鼻腔功能(鼻气道阻力、嗅觉)的改善情况。结果:试验组和对照组主观症状及客观鼻腔功能检查均有改善,但试验组显著高于对照组,差异有统计学意义(P<0.05);2组患者均无不良反应发生。结论:鼻用纤维素粉末用于治疗AR的临床疗效显著,无不良反应发生,有利于改善患者鼻塞、鼻痒、喷嚏等不适症状和提高患者生活质量,值得临床推广使用。

Objective：To investigate the clinical efficacy of nasal cellulose powder for the treatment of allergic rhinitis.Method：Thirty-six cases of patients with allergic rhinitis were randomly divided into control group and experimental group,18 cases in each group.The control group was treated with physiological sea water and the experimental group with nasal fibrous powder.In 14,28 days after drug evaluation in patients objective and subjective symptoms and signs improved nasal function（nasal airway resistance,the sense of smell）was compared.Result：The experimental group and the control group of subjective symptoms and objective nasal function were improved,but the experimental group was significantly higher than that of control group,the difference was statistically significant（P〈0.05）;Two groups of patients had no adverse reaction occurred.Conclusion：The clinical curative effect of Nasal cellulose powder used in the treatment of allergic rhinitis is distinct,without adverse reactions,and is conducive to improving patient stuffy nose,nasal itching,sneezing and other symptoms and improve the patients quality of life,is worth clinical use.