结肠清热丸联合结肠补虚丸治疗寒热错杂型结肠炎30例

Jiechang Qingre Pill combined with Jiechang Buxu Pill in Treating Colitis of Intermingled Cold and Heat for 30 Cases

目的观察结肠清热丸联合结肠补虚丸治疗轻中度寒热错杂型溃疡性结肠炎(UC)的临床疗效。方法将60例符合纳入标准的轻中度寒热错杂型溃疡结肠炎患者随机分为治疗组和对照组,治疗组给予结肠补虚丸、结肠清热丸治疗;对照组给予柳氮磺吡啶肠溶片治疗。两组均治疗4周,分析两组治疗前后的综合疗效。结果治疗组临床完全缓解15例,有效13例,无效2例,总有效率93.33%;对照组临床完全缓解8例,有效12例,无效10例,总有效率66.67%。经统计学分析,总有效率治疗组明显优于对照组(P<0.05)。结论结肠清热丸联合结肠补虚丸治疗轻中度寒热错杂型UC的临床疗效明显优于对照组。

Objective To observe the clinical effect of Jiechang Qingre pill combined with Jiechang Buxu pill in treating ulcerative colitis of intermingled cold and heat. Methods 60 cases of patients with mild to moderate ulcerative colitis of intermingled cold and heat were selected and divided into treatment group and control group, and each group had 30 cases. The treatment group was treated with Jiechang Qingre pill combined with Jiechang Buxu pill. The control group was treated with Sulfasalazine tablets for 4 weeks. The synthetic curative effect was observed and compared between the treatment group and the control group. Results In the treatment group, 15 cases were cured, 13 cases were effectual, 2 cases were unfruitful, and the total effective rate was 93.33 %. As for the control group, 8 cases were cured, 12 cases were effectual, 10 cases were unfruitful, and the total effective rate was 66.67 %. There was significantly difference between the two groups on the synthetic curative effect, and the total effective rate of the treatment group was superior to the control group（P〈0.05）. Conclusion Jiechang Qingre pill combined with Jiechang Buxu pill in treating ulcerative colitis of intermingled cold and heat had certain advantages in the clinical symptom improvement.