疏肝解郁胶囊联合心理干预治疗脑卒中后抑郁

Soothing liver and relieving depression capsules in combined with psychological intervention in treating post-stroke depression

目的探讨疏肝解郁胶囊联合心理干预在脑卒中后抑郁治疗中的作用及安全性。方法选取收治的脑卒中后抑郁患者60例,随机分为治疗组与对照组,各30例,治疗组在常规治疗的基础上加用疏肝解郁胶囊联合心理干预治疗,对照组仅给予常规治疗,观察2组治疗前后汉密尔顿抑郁量表(HAMD)、分析卒中量表(NIHSS)、日常生活活动能力量表(BI)评分改善情况、临床疗效及不良反应。结果 2组治疗后HAMD、NIHSS及BI评分均较治疗前显著下降(P<0.05);治疗组治疗后HAMD、NIHSS及BI评分显著低于对照组(P<0.05);治疗组总有效率96.67%,高于对照组的76.67%(P<0.05)。结论疏肝解郁胶囊联合心理干预可有效缓解脑卒中后抑郁症状,提高患者生活质量。

Objective To explore the effect of soothing liver and relieving depression capsules in combined with psychological intervention on post-stroke depression and its safety. Methods A total of 60 post-stroke depression patients who were admitted in our hospital were included in our hospital and randomized into the treatment group and the control group. Based on the routine treatment,the patients in the treatment group were given soothing liver and relieving depression capsules in combined with psychological intervention,while the patients in the control group were only given routine treatment. The improvements of HAMD,NIHSS,and BI,the clinical efficacy,and the adverse reactions before and after treatment in the two groups were observed. Results The HAMD,NIHSS,and BI scores after treatment in the two groups were significantly reduced when compared with those before treatment（ P〈0. 05）. The HAMD,NIHSS,and BI scores after treatment in the treatment group were significantly lower than those in the control group（ P〈0. 05）. The total effective rate in the treatment group 96. 67% was significantly higher than that in the control group 76. 67%（ P〈0. 05）. Conclusion The combination of soothing liver and relieving depression capsules and psychological intervention can effectively relieve the post-stroke depression,so that the patients＇ living qualities can be enhanced.